https://www.ceesdekker.net - An Overview
https://www.ceesdekker.net - An Overview
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Rotary motion of DNA rotors on nanopores. Top row: Uncooked video of the Cy5 channel of every rotor. Middle row: corresponding solitary-particle localization results of both equally ends of your DNA rotors. The place of the present frame is marked as orange and blue dots, as well as trajectory of the 10 frames right before The present body is proven as stable lines.
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, Groningen scientists current the effects in their initiatives for making labs more sustainable and supply guidelines for other labs.
Given that 2000, Dekker has shifted the most crucial concentrate of his operate towards biophysics in which he scientific tests the Attributes of single biomolecules and cells using the equipment of nanotechnology. This alteration of field was pushed by his fascination for that extraordinary functioning of biological molecular structures, and also because of the long-term viewpoint that lots of appealing discoveries is usually expected Within this area.[5] Existing traces of exploration in his biophysics team are in the areas of:[6]
That could be a desire of mine and we set to operate with a delightful dose of naivety. This is often something that will probably generate magnificent leads to the for a longer period term, but that does not make any difference. You should not only want to work to the questions of tomorrow, but additionally to the thoughts from the day soon after tomorrow.’
Our investigation ranges with the biophysics of DNA to artificial cells and over and above. Remember to take a look down below within the spectrum of our present-day jobs.
We use nanofabricated microfluidic constructions to pattern spatial boundaries for germs and biomimetic vesicles with reconstituted protein networks and this assess the fundamental role of spatial confinement at the molecular and mobile stage. Our initiatives include things like the next:
2000, discovery that nanotubes can have extraordinary massive present-day densities; settled the controversial challenge of Digital transport by way of DNA molecules by measurements of insulating actions at The only molecule stage; and demonstration of the AFM method for solitary-molecule manipulation of nanotubes
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Dekker started off his analysis on single carbon nanotubes in 1993 when he arrange a completely new line of investigation to study electrical transportation by means of single organic https://www.ceesdekker.net and natural molecules among nanoelectrodes. In 1996 a breakthrough was realized with carbon nanotubes. This was realized within a collaboration Using the team of Nobel laureate Richard Smalley. STM and nanolithography strategies were being accustomed to demonstrate that these nanotubes are quantum wires at The only-molecule level, with remarkable physical Attributes.
FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in bacterial cell division
Later on we spoke all over again briefly since Dekker felt that our dialogue of his religion immediately became purely philosophical, whereas Furthermore, it concretely allows him in his function.
Developments in nanotechnology while in the nineties manufactured making Digital products from one molecules a probability. Cees Dekker recounts how his workforce established a home-temperature transistor based on a single carbon nanotube.
Example (2) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is shown in gray, the rim in the pore is highlighted in red, and also a 3D rendering with the motion of your DNA rod is shown.